6/19/2023 0 Comments Taurine pregnancy![]() ![]() Here, the participants will be measured for their eligibility and taken through the consent form. Once they get in contact with the lab, an initial visit (pre-study) will take place. The investigators will recruit healthy pregnant women aged 20 to 40 in their 13th-19th week of gestation or 33rd to 39th week of gestation. Since this study is the first interested in phenylalanine requirements during pregnancy, the investigators will determine the phenylalanine requirements in the presence of excess tyrosine (61 mg/kg/d) during pregnancy, similar to earlier studies. The DRI gives a recommendation for total aromatic amino acids (TAA, phenylalanine + tyrosine) of 36 mg/kg/d during pregnancy. Together they are referred to as the aromatic amino acids. In addition, phenylalanine is the precursor for tyrosine, which is a conditionally indispensable amino acid. Whether phenylalanine requirements differ between different stages of gestation is unknown. Static recommendations throughout all stages of pregnancy are not appropriate because of the multitude of adaptations the human body goes through during gestation. The investigators also hypothesize that the phenylalanine requirements at early stages of pregnancy will be lower than the requirements towards the later stages of pregnancy.Ĭurrent dietary intake recommendations for phenylalanine are based on factorial (mathematical) calculations and do not account for requirement differences between early and late pregnancy. The hypothesis is that the current recommendations for phenylalanine intake given to pregnant women are underestimated. The determined requirements can be taken into account when giving dietary recommendations, to ensure healthy pregnancies. ![]() The investigator's purpose is to determine the phenylalanine requirements in healthy pregnant women as part of a Master's Thesis project. Why Should I Register and Submit Results?.
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